Detection of tuberculosis and infection by Mycobacterium...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

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C435S029000, C435S041000, C424S009100, C424S009200, C424S184100, C424S248100, C424S278100, C530S300000, C530S350000

Reexamination Certificate

active

07833699

ABSTRACT:
The present invention concerns methods for in vitro detection of an infection byMycobacterium tuberculosisin mammals, and methods for in vitro distinction between mammals infected withMycobacterium tuberculosisin which the disease is declared (active form) and mammals which are infected but asymptomatic for tuberculosis (latent form), and a method for in vitro distinction between mammals presenting an active form of tuberculosis and mammals not infected byM. tuberculosisor presenting a latent form of tuberculosis. The present invention also pertains to kits for detection and distinction between infected mammals presenting tuberculosis symptoms and infected mammals with no disease development, and a kit for distinguishing between mammals presenting an active form of tuberculosis and mammals not infected byM. tuberculosisor presenting a latent form of tuberculosis.

REFERENCES:
patent: WO-97/44463 (1997-11-01), None
patent: WO-02/054073 (2002-07-01), None
Masungi et al., Journal of Infectious Diseases, vol. 185, No. 4, Feb. 15, 2002, pp. 513-520.

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