Detection of synthetic oligonucleotides extracted from body flui

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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C12Q 168

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active

055589928

ABSTRACT:
The invention provides a method for detecting specific synthetic oligonucleotides that are present in body fluid or tissue samples taken from an animal or human patient to whom oligonucleotides have been administered.

REFERENCES:
patent: 4483920 (1984-11-01), Gillespie et al.
Hanes et al, Nucleic Acid Hybridization, CRL Prevs, 1985, pp. 176-177.
Stein et al, Science, v. 261, Aug. 20, 1993 pp. 1004-1012.
Agrawal et al., Proc. Natl. Acad. Sci. USA 88, 7595-7599 (1991).

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