Detection of synthetic oligonucleotides extracted from body flui

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

336 243, C12Q 168

Patent

active

056934661

ABSTRACT:
The invention provides a method for detecting specific synthetic oligonucleotides that are present in body fluid or tissue samples taken from an animal or human patient to whom oligonucleotides have been administered.

REFERENCES:
patent: 4483920 (1984-11-01), Gillespie et al.
patent: 5118605 (1992-06-01), Urdea
patent: 5149798 (1992-09-01), Agrawal et al.
patent: 5223402 (1993-06-01), Abbas et al.
U.S. Patent application 08/002,786, Temsamani et al.
Seibl et al. Non-radioactive Labeling and Detection of Nucleic Acids III. Applications of the Digoxigenin System, Biol. Chem. Hoppe-Seyler (Oct. 1990) 371:939-951.
Agrawal et al. in Gene Regulation: Biology of Antisense RNA and DNA (Erikson and Izant, eds.) Raven Press Ltd., New York (1992) pp. 273-283).
Agrawal (1992) Trends in Biotechnology 10:152-158.
Matsukura et al. in Prospects for Antisense Nucleic Acid Therapy of Cancer and AIDS, Wiley-Lisss, Inc. (1992) pp. 159-178.
Agrawal (1991) in Prospects for Antisense Nucleic Acid Therapy of Cancer and AIDS, (Wickstrom, ed.) Liss, New York, pp. 143-158.
Agrawal et al. (1991) Proc. Natl. Acad. Sci (USA) 88:7595-7599.
Vickers et al. (1991) Nucleic Acids. Res. 19:3359-3368.
Agrawal et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:7790-7794.
Matsukura et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:4244-4248.
Agrawal et al. (1988) Proc. Natl. Acad. Sci. (USA) 85:7-7079-7083.
Goodchild et al. (1988) Proc. Natl. Acad. Sci. (USA) 85:5507-5511.
Matsukura et al. (1988) Gene 72:343-347.
Sarin et al. (1988) Proc. Natl. Acad. Sci. (USA) 85:7448-7451.
Wickstrom (1986) J. Biochem. Biophys. Meth. 13:97-102.
Zamecnik et al. (1986) Proc. Natl. Acad. Sci. (USA) 83:4143-4147.
Southern (1975) J. Mol. Biol. 98:503-517.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Detection of synthetic oligonucleotides extracted from body flui does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Detection of synthetic oligonucleotides extracted from body flui, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of synthetic oligonucleotides extracted from body flui will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-800147

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.