Detection of single base mutations and other variations in doubl

Details Detection of single base mutations and other variations in doubl Detection of single base mutations and other variations in doubl

1995-06-06

1999-02-23

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

205456, 205461, 205469, 205450, C12Q 168, C25D 362

Patent

active

058742123

ABSTRACT:
Simple methods of detecting single base pair mutations and other mutations in nucleic acid sequences are provided comprising generating a sample which may comprise heteroduplexes and homoduplexes and performing gel electrophoresis on the sample. The sample may be analyzed for one or more isolated high-melting domains prior to performance of gel electrophoresis. Kits are also provided.

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