Detection of proteases secreted from pathogenic microorganisms

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

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07575887

ABSTRACT:
A diagnostic test kit for detecting the presence or absence of a protease (e.g., aminopeptidase) within a test sample is provided. The test kit comprises a substrate that is capable of being cleaved in the presence of the protease to release a compound. The kit also comprises a lateral flow device that comprises a chromatographic medium. The chromatographic medium defines a detection zone within which is contained a first reagent (e.g., diazonium ion) that is capable of reacting with the compound to form a second reagent (e.g., aromatic azo compound). The second reagent exhibits a color that is different than the color of the first reagent. The lateral flow device also includes an absorbent material located adjacent to the chromatographic medium, the absorbent material receiving the test sample after flowing through the chromatographic medium.

REFERENCES:
patent: 3700623 (1972-10-01), Keim
patent: 3772076 (1973-11-01), Keim
patent: 4140580 (1979-02-01), Gibson et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4537657 (1985-08-01), Keim
patent: 4614723 (1986-09-01), Schmidt et al.
patent: 4637979 (1987-01-01), Skjold et al.
patent: 4748116 (1988-05-01), Simonsson et al.
patent: 4806423 (1989-02-01), Hugl et al.
patent: 4814271 (1989-03-01), Hugl et al.
patent: 4859581 (1989-08-01), Nicolson et al.
patent: 4874695 (1989-10-01), Pincus
patent: 5075077 (1991-12-01), Durley, III et al.
patent: 5124254 (1992-06-01), Hewlins et al.
patent: 5252459 (1993-10-01), Tarcha et al.
patent: 5292652 (1994-03-01), Dovey et al.
patent: 5328831 (1994-07-01), Stewart et al.
patent: 5449612 (1995-09-01), Lepargneur et al.
patent: 5464739 (1995-11-01), Johnson et al.
patent: 5464741 (1995-11-01), Hendrix
patent: 5518883 (1996-05-01), Soini
patent: 5571684 (1996-11-01), Lawrence et al.
patent: 5573909 (1996-11-01), Singer et al.
patent: 5585273 (1996-12-01), Lawrence et al.
patent: 5585279 (1996-12-01), Davidson
patent: 5591581 (1997-01-01), Massey et al.
patent: 5637509 (1997-06-01), Hemmilä et al.
patent: 5670381 (1997-09-01), Jou et al.
patent: 5731147 (1998-03-01), Bard et al.
patent: 5786137 (1998-07-01), Diamond et al.
patent: 5922537 (1999-07-01), Ewart et al.
patent: 6004530 (1999-12-01), Sagner et al.
patent: 6022698 (2000-02-01), Chen et al.
patent: 6030840 (2000-02-01), Mullinax et al.
patent: 6197537 (2001-03-01), Rao et al.
patent: 6235464 (2001-05-01), Henderson et al.
patent: 6242268 (2001-06-01), Weider et al.
patent: 6243980 (2001-06-01), Bronstein et al.
patent: 6261779 (2001-07-01), Barbera-Guillem et al.
patent: 6287798 (2001-09-01), James et al.
patent: 6306642 (2001-10-01), Nelson
patent: 6348319 (2002-02-01), Braach-Maksvytis et al.
patent: 6362011 (2002-03-01), Massey et al.
patent: 6402918 (2002-06-01), Schlenoff et al.
patent: 6444423 (2002-09-01), Meade et al.
patent: 6451619 (2002-09-01), Catt et al.
patent: 6468741 (2002-10-01), Massey et al.
patent: 6472141 (2002-10-01), Nikiforov
patent: 6485926 (2002-11-01), Nemori et al.
patent: 6528321 (2003-03-01), Fitzgerald et al.
patent: 6582930 (2003-06-01), Ponomarev et al.
patent: 6585939 (2003-07-01), Dapprich
patent: 6613583 (2003-09-01), Richter et al.
patent: 6623955 (2003-09-01), Matner et al.
patent: 7041469 (2006-05-01), Lawrence et al.
patent: 7094528 (2006-08-01), Song et al.
patent: 2001/0046668 (2001-11-01), Levine et al.
patent: 2002/0127623 (2002-09-01), Minshull et al.
patent: 2003/0073147 (2003-04-01), Alderete et al.
patent: 2003/0108978 (2003-06-01), Ciambrone et al.
patent: 2003/0119073 (2003-06-01), Quirk et al.
patent: 2003/0119202 (2003-06-01), Kaylor et al.
patent: 2003/0119204 (2003-06-01), Wei et al.
patent: 2003/0124739 (2003-07-01), Song et al.
patent: 2004/0002110 (2004-01-01), Boga et al.
patent: 2004/0029205 (2004-02-01), Small, Jr. et al.
patent: 2004/0043502 (2004-03-01), Song et al.
patent: 2004/0043507 (2004-03-01), Song et al.
patent: 2004/0043511 (2004-03-01), Song et al.
patent: 2004/0043512 (2004-03-01), Song et al.
patent: 2004/0081971 (2004-04-01), Yue et al.
patent: 2004/0106190 (2004-06-01), Yang et al.
patent: 2004/0121334 (2004-06-01), Wei et al.
patent: 2004/0121480 (2004-06-01), Wei
patent: 2005/0112703 (2005-05-01), Song
patent: 2005/0112780 (2005-05-01), Song
patent: 2005/0124072 (2005-06-01), Boga
patent: 2005/0136529 (2005-06-01), Yang et al.
patent: 2005/0136550 (2005-06-01), Yang et al.
patent: 2005/0191704 (2005-09-01), Boga et al.
patent: 2005/0220712 (2005-10-01), Wright et al.
patent: 2005/0233368 (2005-10-01), Beall et al.
patent: 2005/0243321 (2005-11-01), Cohen et al.
patent: 2005/0244643 (2005-11-01), Song et al.
patent: 2006/0003336 (2006-01-01), Song et al.
patent: 2006/0003394 (2006-01-01), Song
patent: 2006/0019265 (2006-01-01), Song et al.
patent: 2006/0057661 (2006-03-01), Song et al.
patent: 2006/0127459 (2006-06-01), Huang et al.
patent: 2007/0048182 (2007-03-01), Song et al.
patent: 2007/0048807 (2007-03-01), Song
patent: 2007/0048815 (2007-03-01), Song
patent: 2007/0048816 (2007-03-01), Song
patent: 2007/0134747 (2007-06-01), DiGiammarino et al.
patent: 0698600 (1996-02-01), None
patent: 0864864 (1998-09-01), None
patent: WO 9714028 (1997-04-01), None
patent: WO 03023051 (2003-03-01), None
patent: WO 03023051 (2003-03-01), None
patent: WO 2005066359 (2005-07-01), None
patent: WO 2005098020 (2005-10-01), None
patent: WO 2006079826 (2006-08-01), None
patent: WO 2007096637 (2007-08-01), None
patent: WO 2007128980 (2007-11-01), None
Carricajo et al. “Comparative eveluation of five chromogenic media for detection, enumeration and identification of urinary tract pathogens” Eur J Clin Microbiol Infect Dis 1999, 18:796-803.
Lammers et al. “Comparison of test characteristics of urine dipstick and urinalysis at various test cutoff points” Annals of Emergency Medicine, 2001, 38(5):505-512.
Naglik et al. “Candida albicansproteinases and host/pathogen interactions” Cellular Microbiology, 2004, 6(10):915-926.
L.J. Jones et al.—Quenched BODIPY Dye-Labeled Casein Substrates for the Assay of Protease Activity by Direct Fluorescence Measurement—Published,Analytical Biochemistry 251, 144-152 (1997) Article No. AB972259.
J.M. Steiner et al.—Development and analytic validationof an enzyme-linked immunosorbent assay for the measurement of canine pancreatic lipase immunoreactivity in serum—Published,The Canadian Journal of Veterinary Research 2003; 67:175-182.
H. Rahimi et al.—Monoclonal antibodies againstCandidarugosa lipase—Published,Journal of Molecular Catalysts B: Enzymatic 28(2004) 71-74.
D.A. Schofield et al.—DifferentialCandida albicanslipase gene expression during alimentary tract colonization and infection—Published,FEMS Microbiology Letters 244(2005) 359-365.
F. Stehr et al.,—Expression analysis of theCandida albicanslipase gene family during experimental infections and in patient samples—Published,FEMS Yeast Research 4(2004) 401-408.
Englert et al.—Layered Expression Scanning: Rapid Molecular Profiling of Tumor Samples—Published,Cancer Research 60, 1526-1530, Mar. 15, 2000.
A.W. Kusterbeck et al.- Use of the USDT flow immunosensor for quantitation of benzoylecgonine in urine—Published,Elsevier Science Limited, Biosensors&Bioelectronicsvol. 11 No. 8 pp. 725-734, 1996.
D.J. Pritchard et al.—Simultaneous determination of follicle stimulating hormone and luteinising hormone using multianalyte immunosensor—Published,Elsevier, Analytica Chimica Acta 310(1995) 251-256.
L.M. Golub et al.—A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis—Published,Inflamm. res. 46 (1997) 310-319.
K. Brew et al.—Tissue inhibitors of metalloproteinases: evolution, structure and function—Published,Elsevier—Biochimica et Biophysica Acta 1477(2000) 267-283.
B. Stratmann et al.—MMP-TIMP interaction depends on residue 2 in TIMP-4—Published,FEBS Letters 507(2001) 285-287.
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