Detection of Porphyromonas gingivalis

Details Detection of Porphyromonas gingivalis Detection of Porphyromonas gingivalis

1993-06-02

1995-07-11

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 2432, 536 2433, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104

Patent

active

054320550

ABSTRACT:
The present invention relates to novel compositions comprising P. gingivalis specific oligonucleotides which are useful as primers to amplify particular regions of the genome of P. gingivalis during enzymatic nucleic acid amplification. The invention also provides a method for the detection of P. gingivalis, which may be present in a clinical specimen, using the P. gingivalis-specific primers and enzymatic nucleic acid amplification. The present invention also relates to P. gingivalis-specific oligonucleotides which are useful as probes to facilitate detection of the amplified regions of P. gingivalis DNA.

REFERENCES:
patent: 4977251 (1990-12-01), Salyers et al.
patent: 4994376 (1991-02-01), Zambon et al.
Kato et al. J. Bacteriol (1992) 174:3889-3895.
Dickinson J. Bacteriol (1988) 170:1658-1665.
Choi et al. Infect Immun. (1991) 59:1564-1566.
Kuritza et al., "Enumeration of Polysaccharide-Degrading Bacteroides Species in Human Feces by Using Species-Specific DNA Probes", Applied and Environmental Microbiology, vol. 51, No. 2, Feb. 1986 pp. 385-390.

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