Detection of point mutations in neu genes

Details Detection of point mutations in neu genes Detection of point mutations in neu genes

1986-06-04

1990-06-19

Yarbrough, Amelia Burgess

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435803, 436501, 536 27, 935 9, 935 78, C12Q 168

Patent

active

049353411

ABSTRACT:
Oligonucleotide probes reactive with regions of neu oncogenes of mammalian origin in which the mutation causing activation of such oncogenes is contained are described, as are methods for their use in detecting the presence of neu oncogenes in tumor cells. Antibodies specific for gene products encoded by neu oncogenes are also described.

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