Detection of periodontal pathogens including bacteroides forsyth

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 231, C12Q 168, C07H 2102

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active

057891745

ABSTRACT:
The present invention relates to probes and primers for the detection of periodontal pathogens such as Bacteroides forsythus, Porphyromonas gingivalis, Prevotella intermedia and Prevotella nigrescens. As well, the invention relates to rapid and sensitive methods for the detection and identification of periodontal pathogens from an oral sample taken from a patient. Diagnostic kits for the detection and identification of periodontal pathogens in an oral sample from a patient, are also disclosed.

REFERENCES:
Dzink et al., J. Clin. Periodontal. 15:316-323, 1988.
Loesche et al., J. Clin. Microbiol. 30:418-426, 1992.
Olsvik et al., 1994, Clinical Microbiology reviews 7:43-54.
Moore et al., J. Clin. Periodontol. 18:729-739, 1991.
Socransky et al., J. Periodont. Res. 26: 195-212, 1991.
Welsh et al., Nucleic Acids Res. 18: 7213-7218, 1990.
Williams et al., Nucleic Acids Res. 18:6531-6535, 1990.
Sambrook, J. et al. (1989) Molecular Cloning: A Laboratory Manual, 2d Ed., Cold Spring Harbor Lab., Cold Spring Harbor, N.Y.

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