Detection of nucleic acids to assess risk for bovine...

Details Detection of nucleic acids to assess risk for bovine... Detection of nucleic acids to assess risk for bovine...

2005-07-08

2008-05-06

Strzelecka, Teresa (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C536S023100, C536S024300

Reexamination Certificate

active

07368243

ABSTRACT:
The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.

REFERENCES:
patent: 6033858 (2000-03-01), Bastian
patent: WO 97/34015 (1997-09-01), None
patent: WO 01/42504 (2001-06-01), None
patent: WO 02/079511 (2002-10-01), None
Van Keulen, L.M.J. et al., Veterinary Quarterly, vol. 22, pp. 197-200 (2000).
Brenig, Bertram et al., “Zelluläre Nucleinsäuren im Serum und Plasma als neue diagnostische Werkzeuge”Berl. Münch. Tierärztl. Wschr. 115:122-124 (2002).
Durie, Brian G. M. et al., “RT-PCR Amplicons in the Plasma of Multiple Myeloma Patients,”Acta Oncologica39(7): 789-796 (2000).
Gibson, Toby J., “RuNAway Disease: A two cycle model for transmissible spongiform encephalopathies (TSEs) wherein SINE proliferation drives PrP overproduction,”Genome Biology2(7): preprint0006.1-6.17 (2001).
Tsiu, Nancy B. Y. et al., “Stability of Endogenous and Added RNA in Blood Specimens, Serum, and Plasma,”Clinical Chemistry48(10): 1647-1653 (2002).
Urnovitz, Howard B., “RNAs in the Sera of Persian Gulf War Veterans Have Segments Homologous to Chromosome 22q11.2,”Clinical and Diagnostic Laboratory Immunology6(3): 330-335 (May 1999).

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