Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-08-01
2006-08-01
Ponnaluri, Padmashri (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100, C435S091520, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C436S501000, C436S518000, C536S023100, C536S024300
Reexamination Certificate
active
07083917
ABSTRACT:
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detection phase. The ligation phase utilizes a ligation detection reaction between one oligonucleotide probe, which has a target sequence-specific portion and an addressable array-specific portion, and a second oligonucleotide probe, having a target sequence-specific portion and a detectable label. After the ligation phase, the capture phase is carried out by hybridizing the ligated oligonucleotide probes to a solid support with an array of immobilized capture oligonucleotides at least some of which are complementary to the addressable array-specific portion. Following completion of the capture phase, a detection phase is carried out to detect the labels of ligated oligonucleotide probes hybridized to the solid support. The ligation phase can be preceded by an amplification process. The present invention also relates to a kit for practicing this method, a method of forming arrays on solid supports, and the supports themselves.
REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 4883750 (1989-11-01), Whiteley et al.
patent: 4988617 (1991-01-01), Landegren et al.
patent: 5035996 (1991-07-01), Hartley
patent: 5104792 (1992-04-01), Silver et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5258506 (1993-11-01), Urdea et al.
patent: 5278298 (1994-01-01), Chakraborty et al.
patent: 5288468 (1994-02-01), Church et al.
patent: 5290925 (1994-03-01), Fino
patent: 5314809 (1994-05-01), Erlich et al.
patent: 5324633 (1994-06-01), Fodor et al.
patent: 5352582 (1994-10-01), Lichtenwalter et al.
patent: 5371241 (1994-12-01), Brush et al.
patent: 5391480 (1995-02-01), Davis et al.
patent: 5405783 (1995-04-01), Pirrung et al.
patent: 5407798 (1995-04-01), Martinelli et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5415839 (1995-05-01), Zaun et al.
patent: 5418149 (1995-05-01), Gelfand et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5429807 (1995-07-01), Matson et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5470705 (1995-11-01), Grossman et al.
patent: 5494810 (1996-02-01), Barany et al.
patent: 5510270 (1996-04-01), Fodor et al.
patent: 5512441 (1996-04-01), Ronai
patent: 5516635 (1996-05-01), Ekins et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5527681 (1996-06-01), Holmes
patent: 5536649 (1996-07-01), Fraiser et al.
patent: 5593840 (1997-01-01), Bhatnagar et al.
patent: 5594121 (1997-01-01), Froehler
patent: 5648213 (1997-07-01), Reddy et al.
patent: 5667974 (1997-09-01), Brikenmeyer
patent: 5695934 (1997-12-01), Brenner
patent: 5700637 (1997-12-01), Southern
patent: 5723320 (1998-03-01), Dehlinger
patent: 5731171 (1998-03-01), Bohlander
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5800984 (1998-09-01), Vary
patent: 5834181 (1998-11-01), Shuber
patent: 5837832 (1998-11-01), Chee et al.
patent: 5858659 (1999-01-01), Sapolsky et al.
patent: 5868136 (1999-02-01), Fox et al.
patent: 5876924 (1999-03-01), Zhang et al.
patent: 5912148 (1999-06-01), Eggerding
patent: 5932711 (1999-08-01), Boles et al.
patent: 5942391 (1999-08-01), Zhang et al.
patent: 5981176 (1999-11-01), Wallace
patent: 6027889 (2000-02-01), Barany et al.
patent: 6143495 (2000-11-01), Lizardi et al.
patent: 6156501 (2000-12-01), McGall et al.
patent: 6506594 (2003-01-01), Barany et al.
patent: 6569647 (2003-05-01), Zhang et al.
patent: 6852487 (2005-02-01), Barany et al.
patent: 2003/0175750 (2003-09-01), Barany et al.
patent: 0 357 011 (1989-08-01), None
patent: 0 387 696 (1990-03-01), None
patent: 0 487 104 (1992-05-01), None
patent: 0 601 714 (1994-06-01), None
patent: 0 624 643 (1994-11-01), None
patent: 0 628 640 (1994-12-01), None
patent: WO 89/10977 (1989-11-01), None
patent: WO 90/11372 (1990-04-01), None
patent: WO 90/15070 (1990-12-01), None
patent: WO 91/17239 (1991-11-01), None
patent: WO 92/10558 (1992-06-01), None
patent: WO 92/10566 (1992-06-01), None
patent: WO 92/10588 (1992-06-01), None
patent: WO 92/16655 (1992-10-01), None
patent: WO 93/04199 (1993-03-01), None
patent: WO 93/09250 (1993-05-01), None
patent: WO 93/17126 (1993-09-01), None
patent: WO 93/20227 (1993-10-01), None
patent: WO 93/20236 (1993-10-01), None
patent: WO 93/22680 (1993-11-01), None
patent: WO 93/25563 (1993-12-01), None
patent: WO 94/01446 (1994-01-01), None
patent: WO 94/09022 (1994-04-01), None
patent: WO 94/11530 (1994-05-01), None
patent: WO 94/17206 (1994-08-01), None
patent: WO 94/17210 (1994-08-01), None
patent: WO 95/00533 (1995-01-01), None
patent: WO 95/35390 (1995-12-01), None
patent: WO 96/06190 (1996-02-01), None
patent: WO 96/15271 (1996-05-01), None
patent: WO 97/31256 (1997-08-01), None
patent: WO 98/03673 (1998-01-01), None
patent: WO 00/56927 (2000-09-01), None
Day et al., “Detection of Steroid 21-Hydroxylase Alleles Using Gene-Specific PCR and a Multiplexed Ligation Detection Reaction,”Genomics, 29:152-162 (1995).
Grossman et al., “High-Density Multiplex Detection of Nucleic Acid Sequences: Oligonucleotide Ligation Assay and Sequence-Coded Separation,”Nucleic Acids Research, 22(21):4527-4534(1994).
Jin et al., “Alternating Current Impedance Characterization of the Structure of Alkylsiloxane Self-Assembled Monolayers on Silicon,”Langmuir, 10:2662-2671 (1994).
Cheng et al., “In Situ Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy of Carboxylate-Bearing, Siloxane-Anchored, Self-Assembled Monolayers: A Study of Carboxylate Reactivity and Acid-Base Properties,”Langmuir, 11:1190-1195 (1995).
Kim et al., “Polymeric Self-Assembled Monolayers. 2. Synthesis and Characterization of Self-Assembled Polydiacetylene Mono- and Multilayers,”J. Am. Chem. Soc., 117:3963-3967 (1995).
Lauer et al., “Cloning, Nucleotide Sequence, and Engineered Expression ofThermus thermophilusDNA Ligase, a Homolog ofEscherichia coliDNA Ligase,”Journal of Bacteriology, 173(16):5047-5053 (1991).
Barany et al., “Cloning, Overexpression and Nucleotide Sequence of a Thermostable DNA Ligase-Encoding Gene,”Gene, 109:1-11 (1991).
Jou et al., Deletion Detection in the Dystrophin Gene by Multiplex Gap Ligase Chain Reaction and Immunochromatographic Strip Technology,Human Mutation, 5:86-93 (1995).
Chan et al., “Polymeric Self-Assembled Monolayers. 3. Pattern Transfer by Use of Photolithography, Electrochemical Methods, and an Ultrathin, Self-Assembled Diacetylenic Resist,”J. Am. Chem. Soc., 117:5875-5976 (1995).
Munkholm et al., “Polymer Modification of Fiber Optic Chemical Sensors as a Method of Enhancing Fluorescence Signal for pH Measurement,”Anal. Chem., 58:1427-1430 (1986).
Graham et al., “Gene Probe Assays on a Fibre-Optic Evanescent Wave Biosensor,”Biosensors&Bioelectronics, 7:487-493 (1992).
Chetverin et al., “Sequencing of Pools of Nucleic Acids on Oligonucleotide Arrays,”BioSystems, 30:215-231 (1993).
Pease et al., “Light-Generated Oligonucleotide Arrays for Rapid DNA Sequence Analysis,”Proc. Natl. Acad. Sci. USA, 91:5022-5026 (1994).
Beattie et al., “Advances in Genosensor Research,”Clin. Chem., 41(5) 700-709 (1995).
Bains, “Mixed Hybridization and Conventional Strategies for DNA Sequencing,”Gata, 10(3-4):84-94 (1993).
Kuznetsova et al., “DNA Sequencing by Hybridization with Oligonucleotides Immobilized in a Gel,”Mol. Biol.(Mosk) (Russia), 28(2):290-299.
Lysov et al., “Measurement of Distances Between DNA Segments Increases the Efficiency of Sequencing by Hybridization with Oligonucleotide Matrix,”Molecular Biology, 28(3):433-436 (1994).
Livshits et al., “Dissociation of Duplexes Formed by Hybridization of DNA with Gel-Immobilized Oligonucleotides,”Journal of Biomolecular Structure&Dynamics, 11(4):783
Barany Francis
Barany George
Blok Herman
Hammer Robert P.
Kempe Maria
Board of Supervisors of Louisiana State University and Agricultu
Cornell Research Foundation Inc.
Nixon & Peabody LLP
Ponnaluri Padmashri
Regents of the University of Minnesota
LandOfFree
Detection of nucleic acid sequence differences using the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Detection of nucleic acid sequence differences using the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of nucleic acid sequence differences using the... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3616430