Detection of negatively charged polymers using...

Details Detection of negatively charged polymers using... Detection of negatively charged polymers using...

2011-03-01

2011-03-01

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C549S065000, C548S315100, C536S023100, C536S024300

Reexamination Certificate

active

07897348

ABSTRACT:
Novel methods allowing for the simple optical and electrochemical detection of double-stranded oligonucleotides are disclosed. The methods are rapid, selective and versatile. Advantageously, they do not require any chemical reaction on the probes or on the analytes since they are based on different electrostatic interactions between cationic poly(3-alkoxy-4-methylthiophene) derivatives and single-stranded or double-stranded (hybridized) oligonucleotides.

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