Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-06
1998-09-01
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 435 912, 536 221, 536 231, 536 243, 536 2431, 536 2432, 536 2433, C12Q 170, C12Q 168, C07H 2102, C07H 2104
Patent
active
058009809
ABSTRACT:
Composition including two pathogenic and/or infective agents associated with multiple sclerosis, namely a first agent which consists of a human virus possessing reverse transcriptase activity and related to a family of endogenous retroviral elements, or a variant of the virus, and a second agent, or a variant of the second agent, these two pathogenic and/or infective agents originating from the same viral strain chosen from the strains designated, respectively, POL-2 deposited with the ECACC on Jul. 22, 1992 under Accession Number V92072202 and MS7PG deposited with the ECACC on Jan. 8, 1993 under Accession Number V93010816, and from their variant strains.
REFERENCES:
patent: 4311686 (1982-01-01), Angers et al.
patent: 4346074 (1982-08-01), Gilmour et al.
patent: 4388298 (1983-06-01), Nazerian et al.
patent: 4396600 (1983-08-01), Messineo et al.
patent: 4520113 (1985-05-01), Gallo et al.
patent: 4647773 (1987-03-01), Gallo et al.
patent: 4708818 (1987-11-01), Montagnier et al.
patent: 4900553 (1990-02-01), Silver et al.
patent: 5158976 (1992-10-01), Rosenburg et al.
patent: 5219837 (1993-06-01), Cohen et al.
patent: 5225352 (1993-07-01), Zanetta et al.
patent: 5585262 (1996-12-01), Perron et al.
Perron et al., "Retrovirus Isolation from Patients with Multiple Sclerosis: Epiphenomenon or Causative Factor?", AIDS Research and Human Retroviruses, vol. 8, No. 5, May 1992, p. 922.
Norby, "Viral Antibodies in Multiple Sclerosis", Prog. Med. Virol., vol. 24 1978, pp. 1-39.
Johnson, "Viral Aspects of Multiple Sclerosis", Handbook of Clinical Neurology, vol. 3(47): Demyelinating Diseases, 1985, pp. 319-336.
Cook et al., "Multiple Sclerosis and Distemper in Iceland 1966-1978", Acta Neurol. Scandinav. 61, 1980, pp. 244-251.
Rosati et al. "Incidence of Multiple Sclerosis in the Town of Sassari, Sardinia, 1965 to 1985: Evidence for Increasing Occurrence of the Disease", Neurology 38 (Mar. 1988), pp. 384-388.
Riise et al., "Clustering of Residence of Multiple Sclerosis Patients at Age 13 to 20 Years in Hordaland, Norway", Am J Epidemiol 1991, vol. 133, No. 9, pp. 932-939.
Elian et al., "Multiple Sclerosis Among United Kingdom-Born Children of Immigrants from the Indian Subcontinent, Africa and the West Indies", J Neurol Neurosurg Psychiat, 1990; 53, pp. 906-911.
Lisak et al., "In Vitro Cell-Mediated Immunity of Cerebrospinal-Fluid Lymphocytes to Myelin Basic Protein in Primary Demyelinating Diseases", New Engl. J. Med. 1977, vol. 297, No. 16, pp. 850-953.
Lassmann et al., "Chronic Relapsing Experimental Allergic Encephalomyelitis", Arch. Neurol., 1979, vol. 36, Aug. 1979, pp. 490-497.
Hirayama et al., "Serum-Mediated Oligodendrocyte Cytotoxicity in Multiple Sclerosis Patients and Controls", Neurology 1986, vol. 36, pp. 276-278.
Warren et al., "Diagnostic Value of Cerebrospinal Fluid Anti-Myelin Basic Protein in Patients with Multiple Sclerosis", Ann. Neurol. , vol. 20, No. 1, Jul. 1986, pp. 20-25.
Suzumura et al., "Serum Cytotoxicity to Oligodendrocytes in Multiple Sclerosis and Controls: Assessment by .sup.51 Cr Release Assay", J. Neuroimmunol., 11 (1986), pp. 137-147.
Johnson et al., "Quantitation of the Myelin-Associated Glycoprotein in Human Nervous Tissue from Controls and Multiple Sclerosis Patients", J. Neurochem., vol. 46, No. 4, 1986, pp. 1086-1093.
James, "Multiple Sclerosis or Blood-Brain Barrier Disease", The Lancet, Jan. 7, 1989, p. 46.
Rudge, "Does a Retrovirally Encoded Superantigen Cause Multiple Sclerosis?", J. Neurology Neurosurgery & Psychiatry 1991, vol. 54, pp. 853-855.
Gessain et al., "Intrathecal Synthesis of Antibodies to Human T Lymphotropic Virus Type I and the Presence of IgG Oligoclonal Bands in the Cerebrospinal Fluid of Patients with Endemic Tropical Spastic Paraparesis", J. Infect. Disease, vol. 157, No. 6, Jun. 1988, pp. 1226-1234.
Koprowski et al., "Multiple Sclerosis and Human T-Cell Lymphotropic Retroviruses", Nature, vol. 318, 14 Nov. 1985, pp. 154-160.
Ohta et al., "Sera From Patients with Multiple Sclerosis React with Human T Cell Lymphotropic Virus-I Gag Proteins but Not ENV Proteins-Western Blotting Analysis", J. Immun., vol. 137, Dec. 1, 1986, pp. 3440-3443.
Reddy et al., "Amplification and Molecular Cloning of HTLV-I Sequences from DNA of Multiple Sclerosis Patients", Science, vol. 243, 27 Jan. 1989, pp. 529-533.
Greenberg et al., "Detection of Sequences Homologous to Human Retroviral DNA in Multiple Sclerosis by Gene Amplification", Proc. Natl. Acad. Sci. USA, vol. 86, Apr. 1989, pp. 2878-2882.
Richardson et al., "PCR Analysis of DNA from Multiple Sclerosis Patients for the Presence of HTLV-I", Science, vol. 246, 10 Nov. 1989, pp. 821-824.
Hauser et al., "Analysis of Human T-Lymphotropic Virus Sequences in Multiple Sclerosis Tissue", Nature, vol. 322, 10 Jul. 1986, pp. 176-177.
Karpas et al., "Lack of Evidence for Involvement of Known Human Retroviruses in Multiple Sclerosis", Nature, vol. 322, 10 Jul. 1986, pp. 177-178.
Perron et al., "Leptomeningeal Cell Line from Multiple Sclerosis with Reverse Transcriptase Activity and Viral Particles", Res. Virol., 1989, 140, pp. 551-561.
Perron et al., "Isolations of an Unknown Retrovirus from CSF, Blood and Brain Cells of Patients with Multiple Sclerosis", in Current Concepts in Multiple Sclerosis, Wietholter et al., eds., 1991, Elsevier publ., pp. 111-116.
H. Perron et al., "Isolation of Retrovirus from Patients with Multiple Sclerosis", The Lancet, vol. 337, Apr. 6, 1991, pp. 862-864.
Perron et al., Herpes Simplex Virus ICP0 and ICP4 Immediate Early Proteins Strongly Enhance Expression of a Retrovirus Harboured by a Leptomeningeal Cell Line from a Patient with Multiple Sclerosis, J. Gen. Virol., vol. 74, 1993, pp. 65-72.
Huang, "Defective Interfering Viruses", Fundamental Virology, Fields et al., eds., 1986, pp. 101-117.
Nielsen et al., "Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide", Science, vol. 254, pp. 1497-1500.
Southern, "Detection of Specific Sequences Among DNA Fragments Separated by Gel Electrophoresis", J. Mol. Biol., 1975, vol. 98, pp. 503-517.
Dunn et al., "A Novel Method to Map Transcripts: Evidence for Homology Between an Adenovirus mRNA and Discrete Multiple Regions of the Viral Genome", Cell, vol. 12, Sep. 1977, pp. 23-36.
Perron et al., "In Vitro Transmission and Antigenicity of a Retrovirus Isolated from a Multiple Sclerosis Patient", Res. Virol., vol. 143, No. 5, 1992, pp. 337-350.
Chomczynski et al., "Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction", Anal. Biochem., 1987, vol. 162, pp. 156-159.
Meyerhans et al., "Temporal Fluctuations in HIV Quasispecies in Vivo Are Not Reflected by Sequential HIV Isolations", Cell, vol. 58, Sep. 8, 1989, pp. 901-910.
Linial et al., "Retroviral RNA Packaging: Sequence Requirements and Implications", in Current Topics in Microbiology and Immunobiology. Retroviruses, Strategies of Replication, Swanstrom et al., eds., vol. 157, 1990, pp. 125-152.
Lori et al., "Viral DNA Carried by Human Immunodeficiency Virus Type 1 Virions", J. Virol., vol. 66, No. 8, Aug. 1992, pp. 5067-5074.
Frohman et al., "Rapid Production of Full-Length cDNAs from Rare Transcripts: Amplification Using a Single Gene-Specific Oligonucleotide Primer", Proc. Natl. Acad. Sci. USA, 1988, vol. 85, pp. 8998-9002.
Mallet et al., "Enzyme-Linked Oligosorbent Assay for Detection of Polymerase Chain Reaction-Amplified Human Immunodeficiency Virus Type I", J. Clin. Microbiol., Jun. 1993, vol. 31, No. 6, pp. 1444-1449.
Acha-Orbea et al., "M1s--A Retrovirus Exploits the Immune System", Immunology Today, vol. 12, No. 10, 1991, pp. 356-361.
Asai et al., "J. of Neurochem", vol. 59, No. 1, pp. 307-317, 1992.
ATCC Catalogue of Cell Lines and Hybridomas, Sixth Edition, 1988, pp. 165 and 344-355.
R. Baccala et al., "Genomically Imposed and Somatically Modified Human Thymocyte vb Gene Repertoires", Proc. Natl. Acad. Sci., vol. 88, p. 2908, 1991.
Barna et al., "Human Astrocytes Proliferate in Response to Tumor Necrosis Factor Alpha", J. Neuroimmunol., 30 (1990), pp. 239-243.
Beck et al., "Increased Producti
Bedin Frederic
Beseme Frederic
Mallet Francois
Mandrand Bernard
Perron Herve
Bio Merieux
Fredman Jeffrey
Jones W. Gary
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