Detection of isoniazid resistent strains of M. tuberculosis

Details Detection of isoniazid resistent strains of M. tuberculosis Detection of isoniazid resistent strains of M. tuberculosis

1994-04-18

1997-11-18

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, 435 912, 435 863, 536 243, 536 2433, 536 253, 935 76, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104, C07H 2102

Patent

active

056886390

ABSTRACT:
A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction length polymorphism analysis to determine whether or not the DNA of said strain has an NciI-MspI restriction site at the codon corresponding to codon 463 of an M. tuberculosis katG gene consensus sequence.

REFERENCES:
patent: 4800159 (1989-01-01), Mullis et al.

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