Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-04-07
1997-08-19
Sisson, Bradley L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 435863, 536 237, 536 2432, 536 2433, 935 8, 935 76, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104, C12N 1500
Patent
active
056587333
ABSTRACT:
A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction fragment length polymorphism analysis to determine whether or not the DNA of said strain has an MspI restriction site at the codon corresponding to codons 315 or 463 of an M. tuberculosis katG gene consensus sequence.
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Cockerill, III Franklin R.
Kline Bruce C.
Uhl James R.
Mayo Foundation for Medical Education and Research
Sisson Bradley L.
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