Detection of inherited and somatic mutations of APC gene in colo

Details Detection of inherited and somatic mutations of APC gene in colo Detection of inherited and somatic mutations of APC gene in colo

1994-08-12

1997-07-15

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, 435 912, 536 235, 536 2431, 536 2433, 935 77, 935 78, C07H 2104, C07H 2102, C12P 1934, C12Q 168

Patent

active

056482124

ABSTRACT:
Methods are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. APC is a tumor suppressor.

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