Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-02-26
1996-10-08
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435810, 436501, 536 221, 536 231, 536 243, 536 2431, 536 2432, 935 77, 935 78, C12Q 168
Patent
active
055630332
ABSTRACT:
In situ hybridization methods for assessing, determining or observing the RNA produced by transcriptionally active genes. In one embodiment, the methods allow simultaneous observation of the gene and its transcripts in a spatially correlated manner. As the in situ hybridization methods have established their ability to maintain the targeted mRNA at the site of its transcription, it can be determined which genes are being expressed and the level of expression can be quantitated.
REFERENCES:
patent: 4888278 (1989-12-01), Singer et al.
patent: 5225326 (1993-07-01), Bresser et al.
Xing et al., Science, vol. 259, Feb. 26, 1993, pp. 1326-1330.
Carter et al., Science, vol. 259, Feb. 26, 1993, pp. 1330-1335.
Xing et al., Trends in Cell Biology, vol. 3, No. 10, Oct. 1993, pp. 346-353.
Xing et al., J. Cell Biology, 115, No. 3, Part 2, Nov. 1991, p. 372A, Abstract No. 2162.
Lawrence et al., Cell, vol. 57, No. 3, May 5, 1989, pp. 493-502.
Carter et al., J. Cell Biology, vol. 115, No. 5, Dec. 1991, pp. 1191-1202.
Raap et al. (1991) Eapt. Cell Res., V. 197, pp. 319-322.
Johnson Carol V.
Lawrence Jeanne B.
Xing Yigong
Jones W. Gary
Marschel Ardin H.
The University of Massachusetts Medical Center
LandOfFree
Detection of individual gene transcription does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Detection of individual gene transcription, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of individual gene transcription will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-56168