Detection of hybridized oligonocleotide probes in living cells

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 5, 435 912, 514 44, 536 245, 536 243, 536 2432, 536 2433, C12Q 168, C12Q 170, A61K 4800, C07H 2104

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057285276

ABSTRACT:
A method of nucleic acid hybridization in living cells is described, which is useful for detecting, quantitating and locating a specific nucleic acid in a cell or tissue, for selecting cells based on the expression or presence of a specific nucleic acid, and for monitoring the amount and location of a specific nucleic acid over time or under various inducing or inhibiting conditions.

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