Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2009-04-13
2011-10-25
Kapushoc, Stephen (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S009000, C435S287100, C536S023100, C536S024300
Reexamination Certificate
active
08043805
ABSTRACT:
Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.
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Algeciras-Schimnich Alicia
King Walter
Morrison Larry E.
Seelig Steven A.
Sokolova Irina A.
Farrell Kevin M.
Kapushoc Stephen
Pierce Atwood LLP
Vysis, Inc.
Wilson David J.
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