Detection of electrophilic and nucleophilic chemical agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07449579

ABSTRACT:
A “real time” method for detecting electrophilic and nucleophilic species generally by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species.

REFERENCES:
patent: 5019350 (1991-05-01), Rhum et al.
patent: 5075215 (1991-12-01), Dreyer
patent: 5132206 (1992-07-01), Dreyer
patent: 5354825 (1994-10-01), Klainer et al.
patent: 5945343 (1999-08-01), Munkholm
patent: 6080516 (2000-06-01), Devlin et al.
patent: 6344654 (2002-02-01), Lesko
patent: 6521185 (2003-02-01), Groger et al.
patent: 6623973 (2003-09-01), Levitsky et al.
patent: 6821738 (2004-11-01), Harmon
patent: 2005/0147534 (2005-07-01), Swager et al.
Le et al., Journal of Organic Chemistry, 2004, vol. 69, pp. 2768-2772.
Pavelk, A. S, The Fluorescense Properties of Protoberbine and Tetrahydroprotoberbine Alkaloids, Coll. Czech. Chem. Commun., 1976, 3157, 3169, 41.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Detection of electrophilic and nucleophilic chemical agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Detection of electrophilic and nucleophilic chemical agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of electrophilic and nucleophilic chemical agents will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4030311

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.