Detection of dinucleotide repeat polymorphism in exon 18 of LDL

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435912, C12Q 168, C12P 1934

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056886470

ABSTRACT:
A method detects whether an individual is predisposed to obesity. The method includes the steps of (i) obtaining a sample containing human genomic DNA from the individual; (ii) detecting whether the genomic DNA in the sample has a 7 AT tandem repeat in exon 18 of the low density lipoprotein receptor gene on one or both chromosomes; and (iii) correlating the absence of the 7 AT tandem repeat on the chromosome or chromosomes with a predisposition to obesity in the individual.

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