Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1987-07-31
1990-06-26
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436 64, 436506, 436543, 436813, 436825, 530352, G01N 3353, G01N 33564, G01N 33531, C07K 1500
Patent
active
049371851
ABSTRACT:
A method and kit are described for detecting the presence of cancers and pre-neoplastic cells that produce an oncofetal phosphoprotein having a molecular weight of approximately 60,000 and having the capacity to increase the release of ribonucleic acid from cell nuclei. The method involves detecting the presence of auto-antibodies to this oncofetal phosphoprotein in a subject suspected of suffering from a cancer or pre-neoplastic cells which produce this cancer marker protein. The kit includes purified oncofetal phosphoprotein.
REFERENCES:
patent: 4342566 (1982-08-01), Theofilopoulos et al.
patent: 4594319 (1986-06-01), Sharma
patent: 4743678 (1988-05-01), Essex et al.
Lee et al., Breast Cancer Research and Treatment, vol. 6, 1985, pp. 57-65.
Hanausek-Walaszek et al., Biochemical and Biophysical Research Communications, vol. 127, No. 3, 1985, pp. 779-785.
Reeves et al., Proc. Natl. Acad. Sci. USA, vol. 83, Dec. 1986, pp. 9507-9511.
Hanausek-Walaszek Margaret
Mercurio Frank
Webb Thomas E.
Hoffer Florina B.
Kepplinger Esther M.
Millard Sidney W.
The Ohio State University Research Foundation
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