Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1995-05-31
1998-06-16
Sisson, Bradley L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 435 911, 536 231, 536 2431, 536 2433, 536 253, 935 77, 935 78, C12P 1934, C12Q 168, C07H 2104, C12N 1500
Patent
active
057668884
ABSTRACT:
Methods are provided for detecting carcinoma metastases in selected body tissues and fluids. These methods offer greater than 1,000-fold enhanced sensitivity compared to prior standard diagnostic methods. In one embodiment of the invention, target carcinoma associated nucleic acid sequences are identified for detecting minimal residual disease in lung carcinomas. The methods utilize nucleic acid amplification techniques, preferably, the polymerase chain reaction.
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Green Mark R.
Kawasaki Ernest S.
Sobol Robert E.
Johnston George W.
Petry Douglas A.
Roche Molecular Systems Inc.
Sisson Bradley L.
The University of California
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