Detection of biological molecules using chemical amplification a

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

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600310, A61B 500

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060119845

ABSTRACT:
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.

REFERENCES:
patent: 4401122 (1983-08-01), Clark, Jr.
patent: 4428366 (1984-01-01), Findl et al.
patent: 4496722 (1985-01-01), Gallop et al.
patent: 4655225 (1987-04-01), Daehn et al.
patent: 4680268 (1987-07-01), Clark, Jr.
patent: 4805623 (1989-02-01), Jobsis
patent: 4875486 (1989-10-01), Rapoport et al.
patent: 4882492 (1989-11-01), Schlager
patent: 4974929 (1990-12-01), Curry
patent: 5028787 (1991-07-01), Rosenthal et al.
patent: 5054487 (1991-10-01), Clarke
patent: 5070874 (1991-12-01), Barnes et al.
patent: 5077476 (1991-12-01), Rosenthal
patent: 5086229 (1992-02-01), Rosenthal et al.
patent: 5101814 (1992-04-01), Palti
patent: 5112124 (1992-05-01), Harjunmaa et al.
patent: 5196709 (1993-03-01), Berndt et al.
patent: 5203328 (1993-04-01), Samuels et al.
patent: 5246867 (1993-09-01), Lakowicz et al.
patent: 5279543 (1994-01-01), Glikfeld et al.
patent: 5281825 (1994-01-01), Berndt et al.
patent: 5342789 (1994-08-01), Chick et al.
patent: 5353790 (1994-10-01), Jacques et al.
patent: 5362307 (1994-11-01), Guy et al.
patent: 5409835 (1995-04-01), Lakowicz et al.
patent: 5445611 (1995-08-01), Eppstein et al.
patent: 5458140 (1995-10-01), Eppstein et al.
patent: 5476094 (1995-12-01), Allen et al.
patent: 5495850 (1996-03-01), Zuckerman
patent: 5628310 (1997-05-01), Rao et al.
Hawkins, et al., J. Am. Chem. Soc., 82:3863-3866 (1960).
Guilbault, et al., Anal. Chem., 40:190 (1968).
Monroe, Am. Clin. Lab., 8(12) :8-16 (1989).
DCCT Research Group, N. Engl. J. Med., 329:977-986 (1993).
Lakowicz, et al., Sensors and Actuators B., 11:133-143.
Lakowicz, et al., J. Fluorescence, 4(1) :117-136 (1994).
Bostick et al., "Quantitative Determination of Blood Glucose Using Enzyme Induced Chemiluminescence of Luminol," Analytical Chemistry, pp. 447-452, Mar. 1975.
Pilosof et al., "Microporous Membrane Flow Cell with Nonimobilzed Enzyme for Chemiluminescent Determination of Glucose," Analytical Chemistry, pp. 1698-1701, Nov. 1982.
Sandanayake et al., "Molecular Fluorescence Sensor for Saccharides Based on Amino Coumarin", Chemistry Letters, pp. 139-140, Feb. 1995.
Arnold, et al., Anal. Chem., 62:1457-1464 (1990).
Falasca, et al., Biochimica et Biophysica Acta, 577:71-81 (1979).
Gough, et al., Diabetes, 44:1005-1009 (1995).
James, et al., J. Chem. Soc., Chem. Commun., pp. 477-478 (1994).
James, et al., J. Am. Chem. Soc., 117:8982-8987 (1995).
James, et al., Nature, 374:345-347 (1995).
Lin, et al., J. Org. Chem., 44(25):4701-4703 (1979).
Marquardt, et al., Anal. Chem., 65:3271-3278 (1993).
Nakashima, et al., Chemistry Letters, pp. 1267-1270 (1994).
Reach, et al., Anal. Chem., 64(6):381-386 (1992).
Uziel, et al., Biochem. and Biophys. Res. Commun., 180(3):1233-1249 (1991).
Yoon, et al., J. Am. Chem., 114:5874-5875 (1992).

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