Detection of B-cell neoplasms

Details Detection of B-cell neoplasms Detection of B-cell neoplasms

1984-11-15

1987-10-20

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 91, 4351723, 935 9, C12Q 168, C12P 1934, C12N 1500

Patent

active

047014091

ABSTRACT:
B-cell neoplasm is detected by hybridizing lymphocytic DNA with DNA probes that identify chromosomal translocations between human chromosomes 11 and 18.

REFERENCES:
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patent: 4582788 (1986-04-01), Erlich
Tsujimoto et al, "Clustering of Breakpoints on Chromosome II in Human B-Cell Neoplasms with the t(11,14) Chromosome Translocation", Nature, vol. 315, pp. 340-343 (1985).
Tsujimoto et al, "The t(14;18) Chromosome Translocations Involved in B-Cell Neoplasms Result from Mistakes in VDJ Joining", Science, vol. 229, pp. 1390-1393 (1985).
Tsujimoto et al, "Involvement of the bcl-2 Gene in Human Follicular Lymphoma", Science, vol. 228, pp. 1440-1443, (1985).
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Tsujimoto et al., (1984), Science (in press).
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