Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1989-05-04
1991-10-08
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435 18, 436 97, 436147, 436161, 436164, 436173, 548519, C12Q 100
Patent
active
050553895
ABSTRACT:
Appendicitis can be detected by determining a threshold presence of the urinary pigment uroerythrin, in the urine of persons suspected of having appendicitis. The threshold presence of uroerythrin can be determined by precipitation of a sediment having a pink to red color. Additional qualitative, semiquantitative, or quantitative methods including HPLC (high pressure liquid chromatography), TLC (thin layer chromatography), radioimmunoassay, colorimetric tests, NMR (nuclear magnetic resonance), mass spectrometry, electrophoresis, monoclonal antibody tests, and other enzymatic tests may also be employed to measure uroerythrin levels.
REFERENCES:
Robbins, S., Pathologic Basis of Disease, (W. B. Saunders Company, Philadelphia 1974), p. 975.
Biological Abstracts 67(7): 40011, Min, Y., "Diagnosis and Treatment of Acute Appendicitis . . . ", Korean Cent J Med 33(1): 13-15, 1977.
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Isolation and Identification of the Urinary Pigment Uroerythrin Eur. J. Biochem. 56, 230-244 (1975).
A Handbook of Routine Urinalysis, J. P. Lippincott Company, (Philadelphia) 1983 by Graff, SL. pp. 10-13, 83-84, 90.
Significance of Bile Pigment Determination in the Urine for the Differential Diagnosis of Appendicitis, Azerb. Med., Zh 0 (8), '86.
Clinical Pharmacology and Therapeutics, vol. 15(2), 1974.
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N-Substituted Peptides in Urine in the Postoperative Period Bull. Acad. Pol. Soi. (Biol) vol. 13; 565-567, (1965).
Bar-Or David
Greisman Stewart L.
Kastendieck Jon G.
Appenditech, Inc.
Kepplinger Esther L.
Spiegel Carol A.
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