Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2005-10-04
2005-10-04
Chin, Christopher L. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C435S007100, C435S007900, C435S007920, C435S969000, C435S975000, C436S501000, C436S507000, C436S513000, C436S524000, C436S536000, C436S538000, C436S540000, C436S542000, C436S543000, C436S546000, C436S811000
Reexamination Certificate
active
06951763
ABSTRACT:
Methods of detecting antibodies to one or more glycosphingolipid(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached theron, and the glycosphingolipid(s) of interest linked to the solid-phase reactant by an amide bond between an amino group of the glycosphingolipid of interest and a carbonyl group attached to the solid-phase reactant. The methods of detecting antibodies to glycosphingolipid(s) of interest can be used in methods of diagnosing autoimmune diseases in an individual.
REFERENCES:
patent: 5989829 (1999-11-01), Pestronk
patent: 6077681 (2000-06-01), Pestronk
patent: 6121004 (2000-09-01), Pestronk
patent: 6352831 (2002-03-01), Buschard et al.
patent: 6448023 (2002-09-01), Skinner et al.
Van den Berg, L., et al., “Anti-MAG and Anti-SGPG Antibodies in Neuropathy,”Muscle Nerve, 19(5):637-643 (1996).
Miyatani, N., et al., “Glycosphingolipids in the Cerebrospinal Fluid of Patients with Multiple Sclerosis,”Mol. Chem. Neuropathol., 13(3):205-216 (1990).
Ilyas, A.A., et al., “Antibodies to Sulfated Glycolipids in Guillain-Barre Syndrome,”J. Neurol. Sci., 105(1):108-117 (1991).
Yuki, N., et al., “Correlation Between Cytomegalovirus Infection and IgM Anti-MAG/SGPG Antibody Associated Neuropathy,”Ann. Neurol., 44(3):408-410 (1998).
Yuki, N., et al., “Autoantibodies to Peripheral Nerve Glycosphingolipids SPG, SLPG, and SGPG in Guillain-Barre Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy,”J. Neuroimmunol., 70(1):1-6 (1996).
Hauttecoeur, B., et al., “Reactivity of Human Monoclonal IgM with Nerve Glycosphingolipids,”Clin. Exp. Immunol., 80(2):181-185 (1990).
Younes-Chennoufi, B.A., et al., “Anti-sulfoglucuronyl Paragloboside IgM Antibodies in Amyotrophic Lateral Sclerosis.,”J. Neuroimmunol., 57(1-2):111-115 (1995).
Lauritzen, E., et al., “Peptide dot immunoassay and immunoblotting: Electroblotting from aluminum thin-layer chromatography plates and isoelectric focusing gels to activated nitrocellulose”Electrophoresis, 14:852-859 (1993).
Voet, D., et al.,Biochemistry, p. 227 (1990).
Kertiles Louis P.
Robichaud Normand J.
Athena Diagnostics, Inc.
Chin Christopher L.
Hamilton Brook Smith & Reynolds P.C.
LandOfFree
Detection of antibodies to glycosphingolipids using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Detection of antibodies to glycosphingolipids using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of antibodies to glycosphingolipids using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3448055