Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-04-15
1991-09-24
Saunders, David A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 28, 435810, 435 792, 435 794, 436501, 436513, 436518, 436534, 436813, 436827, G01N 33566, G01N 33574
Patent
active
050513540
ABSTRACT:
The invention is a novel immunoassay method for detection of the immunoglobulin IgA.sub.1 with O-linked oligosaccharides lacking sialic acid in fluid samples, such as blood, serum and plasma. Particuarly, the invention is an immunoassay method which extracts total IgA from fluid samples by reaction with an immobilized anti-IgA antibody, and then detects only the IgA.sub.1 fraction with labeled peanut agglutinin.
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Hass G. Michael
Henslee Jerry G.
Rittenhouse Harry G.
Schenck Jay R.
Abbott Laboratories
Curry Daniel R.
Porembski Priscilla E.
Saunders David A.
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