Detection of 5T4 RNA in plasma and serum

Details Detection of 5T4 RNA in plasma and serum Detection of 5T4 RNA in plasma and serum

2011-06-28

2011-06-28

Lu, Frank W (Department: 1634)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S006120, C435S091100, C435S091510, C536S023100, C536S024300, C536S024330, C536S025300

Reexamination Certificate

active

07968317

ABSTRACT:
This invention provides methods for detecting the presence of malignant or premalignant cells, or trophoblastic cells in a human wherein the malignant, premalignant or trophoblastic cells express 5T4. The methods of the invention detect 5T4 RNA in blood, blood plasma, serum, and other bodily fluids. The inventive methods are useful for detection, diagnosis, monitoring, treatment, or evaluation of neoplastic disease, and for the detection and evaluation of placental tissue in pregnant women.

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