Detection method for amino acid derivatives

Details Detection method for amino acid derivatives Detection method for amino acid derivatives

1988-04-19

1989-09-12

Richman, Barry S.

Chemistry: analytical and immunological testing

Including use of radioactive properties

436 89, 436 92, 436172, G01N 3360, G01N 3368

Patent

active

048659940

ABSTRACT:
A method for detecting amino acid derivatives in which 2-anilino-5-thiazolinone derivatives of amino acids are reacted with radioactive iodine siotope-labeled amino compounds or with fluorescent amino compounds to form phenylthiocarbamyl amino acid derivatives. The phenylthiocarbamyl amino acid derivatives are detected with a high level of sensitivity by a radioactive detector or a fluorescence spectrophotometer.

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patent: 4065412 (1977-12-01), Dreyer
patent: 4153416 (1979-05-01), Bonner et al.
Edman et al., Encyclopedia Biochem., 1 (1007), 20-01.
D. G. Klapper, "Trends in Automated Protein Sequence Analysis," Trac:Trends in Analytical Chemistry, vol. 2, No. 12, Dec. 1983, pp. 267-269.

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