Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Reexamination Certificate
2005-10-11
2009-08-11
Campell, Bruce (Department: 1648)
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Reexamination Certificate
active
07572621
ABSTRACT:
A method of detecting, characterizing and treating viral infection is provided. In particular, a strategy of molecular mimicry is provided for characterizing viral behavior and/or a predisposition for a given viral outcome in vivo. Novel compositions are also provided for detecting, characterizing and treating viral infections.
REFERENCES:
Natale et al., Computer-assisted analysis of molecular mimicry between human papillomavirus 16 E7 oncoprotein and human protein sequences, Immunology and Cell Biology, 2000, 78:580-585.
Maksyutov et al., Searching for Local Similarities between HIV-1 and Human Proteins. Application to Vaccines, Molecular Biology, 2002, 36(3):346-358.
Lou et al., Molecular mimicry: a mechanism for autoimmune injury, FASEB, 1992, 6:840-844.
Kammer et al., Molecular Mimicry of Human Cytochrome P450 by Hepatitis C Virus at the Level of Cytotoxic T Cell Recognition (Journal of Experimental Medicine, 1999, 190(2):169-176.
Chew et al., Severe acute respiratory syndrome coronavirus and viral mimicry, The Lancet, 2003, 361:2081.
Lawson, Evidence for mimicry by viral antigens in animal models of autoimmune disease including myocarditis, Cell and Molecular Life Science, 2000, 57:552-560.
Barnett & Fujinami, “Molecular Mimicry: A Mechanism for Autoimmune Injury,”FASEB6(3):840-844 (1992).
Beck & Barrell, “Human Cytomegalovirus Encodes a Glycoprotein Homologous to MHC Class-I Antigens,”Nature331:269-272 (1988).
Chew et al., “Severe Acute Respiratory Syndrome Coronavirus and Viral Mimicry,”Lancet361:2081 (2003).
Kato et al., “Genetic Drift in Hypervariable Region I of the Viral Genome in Persistent Hepatitis C Virus Infection,”J. Virol. 68(8):4776-4784 (1994).
Natale et al., “Computer-Assisted Analysis of Molecular Mimicry Between Human Papillomavirus 16 E7 Oncoprotein and Human Protein Sequences,”Immunol. Cell Biol. 78:580-585 (2000).
Oleszak, “Molecular Mimicry Between Fc Receptors and Viral Antigens,”Archivum Immunologlae et Therapiae Experimentalis42:83-88 (1994).
Zhao et al., “Molecular Mimicry by Herpes Simplex Virus-Type I: Autoimmune Disease After Viral Infection,”Science279:1344-1347 (1998).
Brown Earl
Hu Yu-wen
Campell Bruce
Canadian Blood Services
Kinsey White Nicole
Nixon & Peabody LLP
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