Radiant energy – Luminophor irradiation
Patent
1991-02-01
1992-11-10
Fields, Carolyn E.
Radiant energy
Luminophor irradiation
2504612, 250302, 2041828, 204299R, G01N 2164
Patent
active
051626543
ABSTRACT:
An apparatus is disclosed to optically determine which of four fluorophores is attached to a band of DNA molecules on an electrophoresis gel. The apparatus includes four separate band pass interference filters and four wedge prisms to create four discrete areas of light on a detector. Digital comparison of the relative intensity of light sensed in the four discrete areas determines the identity of the excited fluorophore.
REFERENCES:
patent: 4649280 (1987-03-01), Holland et al.
patent: 4675095 (1987-06-01), Kambara et al.
patent: 4707235 (1987-11-01), Englert et al.
patent: 4811218 (1989-03-01), Hunkapiller et al.
patent: 4832815 (1989-05-01), Kambara et al.
patent: 4833332 (1989-05-01), Robertson, Jr. et al.
patent: 4874492 (1989-10-01), Mackay
patent: 4879012 (1989-11-01), Kambara et al.
patent: 4881812 (1989-11-01), Ohkubo et al.
patent: 4892638 (1990-01-01), Watanabe et al.
patent: 4904366 (1990-02-01), Tokita et al.
patent: 4909920 (1990-03-01), Sarrine et al.
patent: 4927265 (1990-05-01), Brownlee
patent: 4960999 (1990-10-01), McKean et al.
patent: 5006716 (1991-04-01), Hall
Connell et al., Automated DNA Sequence Analysis, BioTechniques 342, vol. 5, No. 4 (1987).
Drossman et al., High-Speed Separations of DNA Sequencing Reactions by Capillary Electrophoresis, Analytical Chemistry (1990).
Luckey, et al., High Speed DNA Sequencing by Capillary Electrophoresis, Nucleic Acids Research, vol. 18, No. 15 (1990).
Smith et al., Fluorescence Detection in Automated DNA Sequence Analysis, Nature, vol. 321, No. 6071, pp. 674-679 (1986).
Smith, DNA Sequence Analysis: Past, Present, and Future, American Biotechnology Laboratory, vol. 7, No. 5 (May 1989).
Kostichka Anthony J.
Smith Lloyd M.
Dunn Drew A.
Fields Carolyn E.
Wisconsin Alumni Research Foundation
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