Detection and therapy of lesions with biotin/avidin conjugates

Details Detection and therapy of lesions with biotin/avidin conjugates Detection and therapy of lesions with biotin/avidin conjugates

1992-08-21

1996-06-11

Kim, Kay K. A.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

424 141, 424 149, 424 851, 4241831, 4241931, 424 943, 514 21, A61K 3818, A61K 3827, A61K 39385, A61K 3944

Patent

active

055253385

ABSTRACT:
Methods are provided for detecting and/or treating lesions in a patient. The methods use a targeting composition comprised of a biotin and targeting protein conjugate or an avidin and targeting protein conjugate; optionally, a clearing composition comprised of avidin, when the targeting composition is a biotin conjugate, or biotin, when the targeting composition is a avidin conjugate; a detection or therapeutic composition comprised of a conjugate of avidin or biotin with a targeting protein and detection or therapeutic agent; and, optionally, another detection or therapeutic composition comprised of avidin or biotin conjugated to a detection or therapeutic agent. Compositions and kits useful in the methods are also provided.

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