Chemistry: analytical and immunological testing – Process or composition for determination of physical state... – Of crystal or crystalline material
Reexamination Certificate
2008-05-06
2008-05-06
Gakh, Yelena G. (Department: 1797)
Chemistry: analytical and immunological testing
Process or composition for determination of physical state...
Of crystal or crystalline material
C436S015000, C436S055000, C436S086000, C436S174000, C436S180000
Reexamination Certificate
active
07368288
ABSTRACT:
The invention contemplates a method for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization pattern”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. It has been shown that changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. It was also found that both the character of changer in the crystallization patter and the fact of such changes can be used as recognition elements in analysis of protein molecules.
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Bailey Charles L.
Elliott Adam
Morozov Victor
Vsevolodov Nikolai N.
Gakh Yelena G.
George Mason Intellectual Properties, Inc.
Grossman David
Yee David
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