Detection and prevention of mycoplasma hominis infection

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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935 8, 935 77, 935 78, 435 912, 435 915, 4351723, 4352523, 4353201, 536 231, 536 2432, 536 2433, C12Q 168, C12P 1934, C07H 2104

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055958710

ABSTRACT:
The present invention is directed to a rapid and sensitive method for detecting Mycoplasma hominis using M. hominis-specific probes, oligonucleotides or antibodies. In particular a target sequence can be amplified by in vitro nucleic acid amplification techniques, detected by nucleic acid hybridization using the subject probes and oligonucleotides or detected by immunoassay using M. hominis-specific antibodies. M. hominis-specific nucleic acids which do not recognize or hybridize to genomic nucleic acid of other Mycoplasma species are also provided.

REFERENCES:
patent: 4870006 (1989-09-01), Dragon et al.
Lerner, R. A., (1984) Antibodies of Predetermined Specificity in Biology and Medicine, Advances in Immunology 36:1-43.
Pollard-Knight, Technique (1990) 2:113-132.
Brogan et al. Molec & Cellular Probes (1992) 6:411-416.
Roberts et al Israel J. Med Sci (1987) 23:618-620.

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