Detection and/or determination of IgM, IgA, IgD and IgE immunogl

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 7, 435177, 435188, 435810, 23230B, 252408, 424 15, 424 8, 424 12, G01N 3354, C12Q 170, G01N 3316, C12N 996

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active

042924030

ABSTRACT:
The present invention relates to (1) a method for the detection and/or determination of an antigen specific immunoglobulin of a peculiar IgX class, in which X means M, A, D or E, comprising: (a) contacting and reacting the test-medium with either insolubilized anti-IgX against the antigen specific immunoglobulin of a peculiar IgX class to be determined, or antigen binding fragment of this anti-IgX, (2) incubating said contacted and reacted test medium with an antigen for which the immunoglobulin to be determined has specific affinity, and with a labelled antigen binding fragment of an antibody against said antigen, as well as (2) the novel coupling product comprising an antigen immunochemically bound to a labelled antigen binding fragment of an antibody against said antigen, and (3) test kit for the performance of said method (1). The labelling agent is detected and/or determined, which provides qualitative and/or quantitative information about the antigen specific immunoglobulin to be determined.

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