Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-10-23
1993-11-02
Hill, Jr., Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 34, 435 35, 4353171, 436 63, 436501, 536 2432, C12Q 168
Patent
active
052582833
ABSTRACT:
Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA with a DNA probe containing DNA sequences that specifically hybridize with C. burnetii DNA of strains associated with the capacity to cause acute or chronic disease.
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Baca Oswald G.
Frazier Marvin E.
Mallavia Louis P.
Samuel James E.
Battelle (Memorial Institute)
Hill Jr. Robert J.
Scheiner Laurie
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