Detecting intrinsic factor blocking site antibody

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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424 96, 424201, 435 4, 435177, 436501, 436527, 436804, G01N 3358, G01N 3382, G01N 3350

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active

044475284

ABSTRACT:
A radioassay procedure and reagent kit therefor for detecting auto blocking antibody, such as auto blocking antibody which interferes with the complexation of intrinsic factor with vitamin B.sub.12. A receptor, i.e., intrinsic factor, is immobilized on a support and the amount of ligand, i.e., vitamin B.sub.12, capable of binding therewith in the presence of a biological fluid sample is determined.

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