Detecting interactions at biomimetic interfaces with liquid...

Stock material or miscellaneous articles – Liquid crystal optical display having layer of specified... – With bonding or intermediate layer of specified composition

Reexamination Certificate

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C436S501000, C436S805000, C435S007100, C349S058000, C252S299010, C427S002110, C427S002130

Reexamination Certificate

active

07125592

ABSTRACT:
A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is in a holding compartment of a substrate, and the receptor molecule is adsorbed on the top surface of the liquid crystal forming an interface between the liquid crystal and the aqueous solution. The receptor molecule is different than the surfactant. A method of detecting a compound in a flowing stream includes passing an aqueous solution over a top surface of a liquid crystal in a holding compartment of a substrate. The method also includes determining whether a change in the orientation of the liquid crystal occurs as the aqueous solution is passed over the top surface of the liquid crystal. A change in the orientation of the liquid crystal indicates the presence of the compound in the flowing stream.

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