Detecting interactions at biomimetic interfaces with liquid...

Details Detecting interactions at biomimetic interfaces with liquid... Detecting interactions at biomimetic interfaces with liquid...

2011-08-02

2011-08-02

Wu, Shean C (Department: 1722)

Liquid crystal cells, elements and systems

Particular structure

Holder, support, frame, or housing

C349S199000, C436S501000, C436S805000, C435S007100, C428S001100

Reexamination Certificate

active

07990488

ABSTRACT:
A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is in a holding compartment of a substrate, and the receptor molecule is adsorbed on the top surface of the liquid crystal forming an interface between the liquid crystal and the aqueous solution. The receptor molecule is different than the surfactant. A method of detecting a compound in a flowing stream includes passing an aqueous solution over a top surface of a liquid crystal in a holding compartment of a substrate. The method also includes determining whether a change in the orientation of the liquid crystal occurs as the aqueous solution is passed over the top surface of the liquid crystal. A change in the orientation of the liquid crystal indicates the presence of the compound in the flowing stream.

REFERENCES:
patent: 6456355 (2002-09-01), Choi et al.
patent: 7125592 (2006-10-01), Abbott et al.
patent: 7459124 (2008-12-01), Abbott et al.
patent: 7724319 (2010-05-01), Abbott et al.

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