Detecting immunological changes in HIV infected patient samples

Details Detecting immunological changes in HIV infected patient samples Detecting immunological changes in HIV infected patient samples

1989-07-13

1992-10-20

Nucker, Christine

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 79, 435 792, 435975, 435 5, 436548, G01N 3353

Patent

active

051569515

ABSTRACT:
The present invention comprises a method for detecting immunological changes in blood samples from patients infected with HIV. The method comprises the use of fluorescently labelled monoclonal antibodies against IL-2R (CD25). Other antibodies, including anti-CD3, anti-CD38 and anti-HLA DR antibodies also may be used. It has been found that a decrease in expression of CD25 in such samples indicates HIV infection.

REFERENCES:
patent: 3826364 (1974-07-01), Bonn et al.
patent: 4284412 (1981-08-01), Hansen et al.
patent: 4452773 (1984-06-01), Molday
patent: 4520110 (1985-05-01), Stryer et al.
patent: 4607007 (1986-08-01), Lanier et al.
patent: 4628026 (1986-12-01), Gardell et al.
patent: 4661913 (1987-04-01), Wu et al.
patent: 4677061 (1987-06-01), Rose et al.
patent: 4717655 (1988-01-01), Fulwyler
patent: 4727020 (1988-02-01), Recktenwald
Daniel et al: Lymphocyte autoantibodies . . . patients Clin Exp Immunol. 75(2) pp. 178-183 Feb. 89 Abstract Only-
Redfield et al., Sc. Amer., 259:70 (1980).
Vchiyana et al., J. Immunol., 126:1393 (1981).
Schulman et al., Natura, 276:269 (1978).
Herzenberg et al., Sci. Amer., 234:108 (1976).
Lewis et al., J. Infect. Diseases, 151:555 (1985).
Honda et al., J. Immunol., 142:4248 (1989).
Stites et al., Clin. Immunol. Immunopath., 38:161 (1986).
Clerici et al., Nature, 339:383 (1989).
Kohler et al., Eur. J. Immunol. 6:511 (1976).

Affiliated with

Also associated with

Rating

Detecting immunological changes in HIV infected patient samples does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Detecting immunological changes in HIV infected patient samples, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detecting immunological changes in HIV infected patient samples will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-191351