Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-08-03
1997-11-11
Myers, Carla J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 435810, 536 235, 536 2431, 536 2433, 436 63, 935 77, 935 78, 935 8, C12Q 168, C12P 1934, C07H 2104
Patent
active
056862466
ABSTRACT:
A method and kit for the identification of a patient's genetic polymorphism pattern associated with increased periodontal disease severity is disclosed. The kit includes DNA sample collecting means and means for determining a genetic polymorphism pattern which is then compared to control samples to determine a patient's susceptibility to severe periodontal disease.
REFERENCES:
patent: 4582788 (1986-04-01), Erlich
patent: 4666828 (1987-05-01), Gusella
patent: 4738927 (1988-04-01), Taniguchi et al.
patent: 4772685 (1988-09-01), Schmidt et al.
patent: 4801531 (1989-01-01), Frossard
patent: 4992367 (1991-02-01), Cullen
patent: 5110920 (1992-05-01), Erlich
patent: 5158871 (1992-10-01), Rossomando et al.
patent: 5206344 (1993-04-01), Katre et al.
patent: 5215895 (1993-06-01), Bennett et al.
patent: 5268267 (1993-12-01), Smith
patent: 5272057 (1993-12-01), Smulson et al.
patent: 5328829 (1994-07-01), Stashenko
Blakemore et al., "Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic Lupus erythematosus" Arthritis and Rheumatism 37(9):1380-1385 (1994).
Clark et al., "Genomic sequence for human prointerleukin 1 beta: possible appears in Nucleic Acids Res., 15(2):868 (1987)!.
de Giovine et al., "Single base polymorphism at--511 in the human interleukin-1.beta. gene (IL1.beta.)" Human Molecular Genetics 1, No. 6:450 (1992).
Duff, "Cytokines and anti-cytokines" Br. J. Rheumatol. 32 (Suppl 1):15-20 (1993).
Furutani et al., "Complete nucleotide sequence of the gene for human interleukin 1 alpha" Nucl Acids Res., 14:3167-3179 (1986).
Mansfield et al., "Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin 1 receptor . . . " Gastroenterology, 106:637-642 (1994).
McDowell et al., "A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1.alpha. polymorphism" Arthritis & Rheumatism, vol. 38, No. 2, pp. 221-228 (1995).
McGuire et al., "Variation in the TNF-.alpha. promoter region associated with susceptibility to cerebral malaria" Nature, 371:508-511 (1994).
Michalowicz et al. "Periodontal findings in adult twins" J Periodontol, 62:293-299 (1991).
Oppenheim et al., "Cytokines" Basic and Clinical Immunology, 8th ed., eds Stites, Terr & Parslow Chaper 9, pp. 105-123 (1994).
Verjans et al., "Polymorphism of the tumor necrosis factor region in relation to disease: an overview" Rheum Dis Clin North Am, 18:177-186 (1992).
Wilson et al., "Single base polymorphism in the human tumour necrosis factor alpha (TNF.alpha.) gene . . . " Human Molecular Genetics 1, No. 5:353 (1992).
Woolf, "On estimating the relationship between blood group and disease" Annals of Human Genetics, 19:251-253 (1955).
Anusaksathien, O. and A.E. Dolby, "Autoimmunity in periodontal disease", J. Oral Pathol. Med., 20:101-1-7 (1991).
Anusaksathien, O. et al., "Autoimmunity to collagen in adult periodontal disease: Immunoglobulin classes in sera and tissue", J. Periodont. Res., 27:55-61 (1992).
Dalboge, H. et al., "Cloning and expression of an interleukin-1-.beta. precursor and its conversion to interleukin-1.beta.", FEBS Letters, 246:89-93 (1989).
Hirsch, H.Z. et al., "Autoimmunity to collagen in adult periodontal disease", J. Oral Path., 17(9):456-459 (1988).
Jandinski, J.J. et al., "Localization of interleukin 1.alpha. and tumor necrosis factor .alpha. in human gingiva", J. Dental Res., 68 (Special Issue), Abstract #526 (1989).
Jandinski, J.J. et al., "Localization of interleukin 1-beta in human periodontal tissue", J.Periodontol., 18:703-707 (1991).
Jonsson, R. et al., "Immunoglobulin isotype distribution of locally produced autoantibodies to caollagen type I in adult periodontitis", J. Clin. Periodontol., 18:703-707(1991).
Kjeldsen, M. et al., "Marginal Periodontitis and Cytokines: A Review of the Literature", J. Periodontol., 64(11):1013-1022 (1993).
Lamster, L.B. et al., "Host Mediators in Gingival Crevicular Fluid: Implications for the Pathogenesis of Periodontal Disease", Critical Rev. in Oral Biol. and Med., 3(1/2):31-60 (1992).
Masada, M.P. et al., "Measurement of interleukin-1 alpha and -1 beta in gingival crevicular fluid: implications for the pathogenesis of periodontal disease", J. Period. Res., 25(3): 156-163 (1990).
Pociot, F. et al., "A TaqI polymorphism in the human interleukin 1-.beta. (1L-1.beta.) gene correlates with 1L-1.beta. secretion in vitro", Eur. J. Clin. Invest., 22(396-402) (1992).
Ranney, R.R., "Immunological mechanisms of pathogenesis in periodontal diseases: An assessment", J. Period. Res., 26:243-254 (1991).
Snyderman, R. and G.A. McCarty, "Analogous mechanisms of tissue destruction in rheumatoid arthritis and periodontal disease", In: Host Parasite Interactions in Periodontal Disease, Eds. R.J. Genco and S.E. Mergenhagen, American Society for Microbiology, Washington, D.C. (1982).
Sosroseno, W. et al., "The Interleukin Network in the Immunopathogenesis of Oral Diseases", Asian Pacific J. Allergy and Immunol., 156:296-309 (1994).
Takeichi, O. et al., "Human Polymorphonuclear Leukocytes Derived from Chronically Inflamed Tissue Express Inflammatory Cytokines in vivo", Cellular Immunol., 156: 269-309 (1994).
Wilton, J.M. et al., "Interleukin-1 beta and IgG subclass concentrations in gingival crevicular fluid from patients with adult periodontitis", Arch Oral Biol., 38(1):55-60 (1993).
Wilton, J.M.A. et al., "Interleukin-1 beta (1L-1.beta.) levels in gingival crevicular fluid from adults with previous evidence of destructive periodontitis", J. Clin. Periodontol. 19(1)53-57 (1992).
Duff Gordon W.
Kornman Kenneth S.
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