Detecting genetic predisposition for osteoporosis

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, C12Q 168, C12P 1934

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056983999

ABSTRACT:
The present invention relates to methods of predicting the risk of osteoporosis. Specifically, the methods comprise isolating genomic DNA from an individual and determining an allelic pattern for IL-1 receptor antagonist (IL-1ra) in the genomic DNA. The identification of at least one copy of allele 2 indicates increased susceptibility to osteoporosis.

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