Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-06-07
1999-11-23
Myers, Carla J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 15, 435 912, 435 72, 536 2431, 536 2433, C12Q 168, C12P 1934, C07H 2104
Patent
active
059898070
ABSTRACT:
Methods and kits are provided for diagnosis of specific cancerous conditions. The invention features a method for diagnosis of a condition in a patient associated with an elevated level of telomerase activity within a cell. The method involves determining the presence or amount of telomerase within the cells in the patient, e.g. by the use of the polymerase chain reaction. In one embodiment of the invention, the condition associated with elevated telomerase activity is chosen from prostate cancer, breast cancer, colon cancer, renal cancer, ovarian/cervical cancer, lung cancer, and leukemia. The invention allows cancer to be detected even in tissues and cells which are not positive by pathology.
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Harley Calvin B.
Kim Nam Woo
Shay Jerry
Weinrich Scott L.
West Michael D.
Geron Corporation & Board of Regents
Myers Carla J.
The University of Texas System
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