Detecting blood clotting factors with immobilized fibrinogen and

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor

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435 28, 435174, 435180, 435184, 435188, 435214, G01N 3353, G01N 3358, G01N 3386

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active

046686215

ABSTRACT:
Assays and reagents for the direct determination of blood factors, as well as complementary methods and reagents for determining such blood factors and haptens, antigens and receptors. The methods involve clot formation due to thrombin activated fibrin formation from insolubilized fibrogen and labeled solubilized fibrogen. Insolubilized label can be determined prior to or after clot formation.

REFERENCES:
patent: 3778352 (1973-12-01), Bishop
patent: 3960669 (1976-06-01), Innerfield
patent: 4011142 (1977-03-01), Jacobi
patent: 4046635 (1977-09-01), Moroz
patent: 4216291 (1980-08-01), Collen
patent: 4463090 (1984-07-01), Harris
Chemical Abstracts, 94:169108t, (1981).

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