Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1996-09-16
1999-08-17
Chan, Christina
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436501, 436518, 436531, G01N 3353
Patent
active
059392819
ABSTRACT:
The present invention relates to devices and methods for detecting cellular products, and in particular for measuring secreted cellular products, including cytokines. Microwells comprising hydrophobic membranes are described having greater capability to detect cytokines from individual cells in a mixture of heterogeneous cells. A method is provided that can serve as a) a functional predictor of allograft survival in transplant recipients, and b) a tool for monitoring the level of immunosuppression in allograft recipients.
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Karulin Alexey
Lehmann Paul V.
Trezza Richard Peter
Case Western Reserve University
Chan Christina
Nolan Patrick
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