Detecting a target using a composite probe comprising a...

Details Detecting a target using a composite probe comprising a... Detecting a target using a composite probe comprising a...

2011-02-22

2011-02-22

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

C435S007720, C424S046000

Reexamination Certificate

active

07892781

ABSTRACT:
A test agent includes a composite probe having at least one nanoparticle having multiple metal atoms, a directing agent, and an enzyme. The directing agent attaches the probe to a target in a test sample. The test sample and bound probe are then treated with an enzyme substrate. A method of detecting a target in a test sample includes exposing the test sample to the probe, then treating the test sample with an enhancement or development solution to deposit at least one of a fluorophore, a chromogen, or a metal.

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