Destruction of contaminating tumor cells in stem cell transplant

Details Destruction of contaminating tumor cells in stem cell transplant Destruction of contaminating tumor cells in stem cell transplant

1997-09-03

1999-11-16

Johnson, Nancy A

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Structurally-modified antibody, immunoglobulin, or fragment...

4241741, 4241301, 4241331, 4241381, 4241441, 4241541, 4241551, 435 11, 435 2, 5303873, 5303877, 53038875, 5303888, 53038885, A61K 39395, C07K 1628, C07K 1630

Patent

active

059852763

ABSTRACT:
The present invention discloses a procedure for the destruction of contaminating tumor cells in stem cell transplants ex vivo using intact bispecific antibodies.

REFERENCES:
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Lindhofer, H. et al. 26th Annual Meeting of the International Society for Experimental Hematology Cannes, France, (Aug. 24-28, 1997) 25(8): 879.
Lindhofer, H. et al. Blood (Dec. 15, 1996) 88(12): 4651-4658.
B. Alberts et al., "The Functional Properties of Antibodies," Molecular Biology of The Cell, Garland Publishing, Inc., p. 965.
M. Balzar et al., Molecular and Cellular Biology (Aug. 1998) 18(8): 4833-4843.
H. Jacobs, Immunology Today (Dec. 1997) 18(12): 565568.

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