Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1986-01-28
1990-09-25
Yarbrough, Amelia B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 7, 4351723, 435320, 436501, 436811, 436813, 935 3, 935 29, 935 56, 935 78, C07H 2104, C12Q 168, C12N 1500, G01N 3353
Patent
active
049594621
ABSTRACT:
This invention relates to DNA having at least 60% homology relative to .gamma.-RNA or a portion thereof and the capacity of selective hybridization with .delta.-RNA. Such DNA, if provided with a detectable label, such as .sup.32 P can be used as a diagnostic agent to diagnose .delta. infection.
REFERENCES:
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patent: 4711955 (1987-12-01), Ward et al.
Tiollais, P. et al. (1985), Nature, 317, pp. 489-495.
Richman, D. D. et al. (1984), J. of Infectious Diseases, 149(3), pp. 298-310.
Chemical Abstracts, vol. 100, No. 21, 21st May 1984, p. 328, col. 1, Abstract No. 171214k, Columbus, Ohio, U.S.; B. Hoyer et al.: "Properties of Delta-Associated Ribonucleic Acid"; & Prog. Clin. Biot. Res., vol. 143, 1983, pp. 92-97.
Chemical Abstracts, vol. 104, No. 21, 26th May 1986, p. 326, cols. 1, 2, Abstract No. 182922y, Columbus, Ohio, U.S., Ne. Cen. Org. voor Toegepast-Natuurwetenschappelijk Onderzoek; "Deoxyribonucleic Acid, Microorganisms, Diagnositc Means for Delta Infection, and Use There Of"; N.A. 8402392 published 17th Feb. 1986, priority 31st Jul. 1984.
Chemical Abstracts, vol. 105, No. 1, 7th Jul. 1986, p. 149, col. 2, Abstract No. 1518y, Columbus, Ohio, U.S.: K. J. Denniston et al.: "Cloned Fragment of the Hepatitis Delta Virus RNA Genome: Sequence and Diagnostic Application"; & Science vol. 232, 1986, pp. 873-875.
Chemical Abstracts, vol. 100, No. 17, 23rd Apr. 1984, p. 481, col. 2, Abstract No. 137082f, Columbus, Ohio, U.S.; F. Bonino et al.: "Delta Hepatitis Agent: Structural and Antigenic Properties of the Delta Associated Particle"; & Infect. Immun., vol. 43, No. 3, 1984, pp. 1000-1005.
Wang et al, Nature, 323, 508-514 (1986).
Denniston et al, The Chemical Abstracts 105:1518y (1986).
Dijkema Reinder
Kos Antonides
Marschel Ardin
Nederlandse Centrale Organisatie voor Toegepast-Natuurwetenschap
Yarbrough Amelia B.
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