Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-03-14
1988-02-02
Fan, Jane T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546335, 546275, 530387, 435 7, C07D40112
Patent
active
047230126
ABSTRACT:
A novel desmosine derivative, which is useful for preparing a desmosine artificial antigen, has an activated, disulfide bond on the side chain at 3 or 5 position of the pyridinium ring. The derivative can combine with a polymer having thiel groups by a disulfide bond to form the effective artificial antigen.
REFERENCES:
Mar. Advanced Org. Chem., p. 21, McGraw-Hill Book Co. _
Darnule et al., "Solid-Phase Radioimmunoassay for Estimation of Elastin Peptides in Human Sera," Analytical Biochemistry (1982); 122:302-307.
Skinner et al., "The Estimation of Elastin in Fetal Tissues by Radioimmunoassay of Isodesmosine," Connective Tissue Research, 1983; 11:113-121.
Davies et al., "Urine Desmosine is Unrelated to Cigarette Smoking or to Spirometric Function," AM REV RESPIR DIS 1983; 128:473-475.
Kucich et al., "Immunologic Measurement of Elastin-Derived Peptides in Human Serum," AM REV RESPIR DIS 1983; 127:S28-S30.
Harel et al., "Desmosine Radioimmunoassay for Measuring Elastin Degradation In Vivo," AM REV RESPIR DIS 1980; 122:769-773.
Matsumoto Takashi
Mizusaki Shigenobu
Okada Takashi
Fan Jane T.
Japan Tobacco Inc.
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