Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Reexamination Certificate
2005-12-28
2010-11-16
Witherspoon, Sikarl A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C549S403000, C514S456000, C514S688000
Reexamination Certificate
active
07834216
ABSTRACT:
This invention discloses the method for preparing desmosdumotin C, the series of desmosdumotin C derivatives and their manufactures, and the total synthesis of desmosdumotin B. The invention also discloses uses of the derivatives and pharmaceutical compositions containing the same in preparation of medicines for treatment of tumor or AIDS.
REFERENCES:
patent: 5411728 (1995-05-01), Joulain et al.
patent: 1098903 (1995-02-01), None
patent: 1126471 (1996-07-01), None
patent: 1335292 (2002-02-01), None
patent: 1611497 (2005-05-01), None
patent: WO 02/089587 (2002-11-01), None
Wu et al. Anti-AIDS Agents 54. A Potent Anti-HIV Chalcone and Flavanoids from Genus Desmos. Biorganic & Medicinal Chemistry Letters, 2003,vol. 13, p. 1813-1815.
Wu et al. Desmosdumotin C, a novel cytotoxic principle fromDesmos dumosus. Tetrahedron Letters 43, 2002, p. 1391-1393.
Nishizawa, et al. “Structure of Syzygiol: A Skin-Tumor Promotion Inhibitor”, Tetrahedron Letters (1991), 32(2), pp. 211-212.
Sbit, et al., “Structure of Ceroptene”, Acta Crystallographica, Section C: Crystal Structure Communications, (1987), C43(11), pp. 2204-2206.
Vilain, et al., “α-Diceroptene: A New Dimeric Structure for Isoceroptene”, Zeitschrift Fuer Naturforschung, C: Journal of Biosciences (1987), 42(7-8), pp. 849-854.
Markham, et al., “Isoceroptene, A Novel Polyphenol from Pityrogramma Triangularis”, Zeitschrift Fuer Naturforschung, C. Journal of Biosciences (1985), 40C(5-6), pp. 317-320.
Dreyer, et al., “Extractives of Dalea Species (Leguminosae)”, Tetrahedron (1975), 31(4), pp. 287-293.
Bick, et al., “Nuclear Magnetic Resonance Studies. V. The Tautomerism of Tasmanone and related β-Triketones”, Australian Journal of Chemistry (1965), 18(9), pp. 1405-1410.
Forsen, “Molecular Orbital Calculations of Some Enolized Di- and Triketones. II. Charge Distributions and Bond Orders. Comparison with Infrared and Proton Magnetic Resonance Data”, Arkiv. Kemi (1962), 20, pp. 25-40.
Forsen, et al., “Proton Magnetic Resonance Studies of Enolized β-Triketones”, Acta Chemica Scandinavica (1959), 13, pp. 1383-1394.
Sato, et al., “Synthesis of Model Compounds of Safflomin C”, Bulletin of the Chemical Society of Japan (1992), 65(2), pp. 452-457.
Sato, et al., “Synthesis of Syzygiol; A Skin-Tumor Promotion Inhibitor”, Bulletin of the Chemical Society of Japan (1992), 65(9), pp. 2552-2554.
Sato, et al., “Efficient Synthesis of Analogs of Safflower Yellow B, Carthamin, and its Precursor: Two Yellow and One Red Dimeric Pigments in Safflower Petals”, Tetrahedron (2005), 61(40), pp. 9630-9636.
Nakagawa-Goto, et al., “First Total Synthesis of Desmosdumotin C”, Synthetic Communications (2005), 35(13), pp. 1735-1739.
Nakagawa-Goto, et al., “Antitumor Agents 243. Syntheses and Cytotoxicity of Desmosdumotin C Derivatives”, Bioorganic & Medicinal Chemistry (2005), 13(6), pp. 2325-2330.
International Search Report for International Application No. PCT/CN2005/002334 mailed Mar. 2, 2006.
Nakagawa-Goto Kyoko
Shi Ning
Wang Xihong
Wu Jiuhong
Pearl Cohen Zedek Latzer LLP
Witherspoon Sikarl A
Wu Jiuhong
LandOfFree
Desmosdumotins, the method for preparing the same and use as... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Desmosdumotins, the method for preparing the same and use as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Desmosdumotins, the method for preparing the same and use as... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4207315